What Are The Factors That Affect Disease Progression
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The most important factor affecting HIV progression is the ability to achieve viral suppression. Taking antiretroviral therapy regularly helps many people slow the progression of HIV and reach viral suppression.
However, a variety of factors affect HIV progression, and some people progress through the phases of HIV more quickly than others.
Factors that affect HIV progression can include:
- Ability to achieve viral suppression. Whether someone can take their antiretroviral medications and achieve viral suppression is the most important factor by far.
- Age when symptoms start. Being older can result in faster progression of HIV.
- Health before treatment. If a person had other diseases, such as tuberculosis, hepatitis C, or other sexually transmitted diseases , it can affect their overall health.
- Timing of diagnosis. Another important factor is how soon a person was diagnosed after they contracted HIV. The longer between their diagnosis and treatment, the more time the disease has to progress unchecked.
- Lifestyle. Practicing an unhealthy lifestyle, such as having a poor diet and experiencing severe stress, can cause HIV to progress more quickly.
- Genetic history. Some people seem to progress more quickly through their disease given their genetic makeup.
Some factors can delay or slow the progression of HIV. These include:
Living a healthy lifestyle and seeing a healthcare provider regularly can make a big difference in a persons overall health.
Viral Load At Different Stages
During the first few weeks after someone gets HIV, viral load is usually very high typically several million viral copies per millilitre of blood . There is a considerable risk of passing on HIV at this point. In fact, many people acquire HIV from someone who has only recently acquired it themselves .
After this period of early infection, viral load usually drops. A typical viral load in someone not taking treatment may be 50,000 copies/ml. There is still a considerable risk of passing HIV on.
After starting HIV treatment, viral load usually falls rapidly. Within three to six months, most peoples viral load has become undetectable.
Most clinics in the UK report a viral load as undetectable if it is below 20-50 copies/ml. However, if your viral load remains below 200 copies/ml , there is no risk of passing HIV to your sexual partners. There is no need to worry if your viral load goes slightly above the detection limit of 20-50 copies/ml.
detectable viral load
When viral load is detectable, this indicates that HIV is replicating in the body. If the person is taking HIV treatment but their viral load is detectable, the treatment is not working properly. There may still be a risk of HIV transmission to sexual partners.
Is There A Cure Or Treatment For Herpes
There is no cure for herpes. Antiviral medications can, however, prevent or shorten outbreaks during the period of time the person takes the medication.11 In addition, daily suppressive therapy for herpes can reduce the likelihood of transmission to partners.11
There is currently no commercially available vaccine that is protective against genital herpes infection. Candidate vaccines are in clinical trials.
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This page is about HIV transmission during sex.
But an undetectable viral load is also crucial for conception, pregnancy and birth. If you maintain an undetectable viral load during pregnancy, the risk of HIV being passed on to your baby is just 0.1%, or one in a thousand.
During breastfeeding, an undetectable viral load greatly reduces the risk of passing HIV on, although it does not completely eliminate this possibility. In the UK and other countries where clean water and sterilising equipment are available, bottle feeding with formula milk is the safest way to feed your baby.
If you use injection drugs and or other equipment, taking HIV treatment and having an undetectable viral load greatly reduces the risk of passing HIV on, but we dont know by how much.
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What Are The Complications Of Genital Herpes
Genital herpes may cause painful genital ulcers that can be severe and persistent in persons with suppressed immune systems, such as HIV-infected persons. 5 Both HSV-1 and HSV-2 can also cause rare but serious complications such as aseptic meningitis . 5 Development of extragenital lesions may occur during the course of infection. 5
Where Can People Find More Information About Hiv Testing
There are several resources for people interested about the facts of HIV testing.
- The national HIV, STD, and hepatitis testing site Get Tested helps visitors find free, fast, and confidential testing.
The CDC web site is also an excellent source of information: https://www.cdc.gov/hiv/basics/testing.html.
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Latency Causes A Break In Symptoms
After initial exposure and possible primary infection, HIV may transition into a stage called clinically latent infection. Its also referred to as asymptomatic HIV infection due to a noticeable lack of symptoms. This lack of symptoms includes possible chronic symptoms.
According to HIV.gov, latency in HIV infection can last for 10 or 15 years. This doesnt mean that HIV is gone, nor does it mean that the virus cant be transmitted to others. Clinically latent infection may progress to the third and final stage of HIV, also referred to as AIDS.
The risk for progression is higher if a person with HIV isnt receiving treatment, such as antiretroviral therapy. Its important to take prescribed medications during all stages of HIV even if there arent any noticeable symptoms. There are several medications used for HIV treatment.
How Well Does The Use Of Hiv Treatment To Maintain An Undetectable Viral Load Prevent Hiv Transmission To A Baby During Pregnancy And Birth
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Without treatment, there is a 15% to 30% chance that a baby born to a person living with HIV will get HIV during pregnancy or delivery. Taking HIV treatment is the most effective way to reduce transmission to the baby. In fact, research has shown that if a pregnant person starts HIV treatment before conception and maintains an undetectable viral load throughout pregnancy and delivery, they do not transmit HIV to their baby. A short course of HIV medications is also given to the infant to prevent HIV transmission.
For the last three decades, a growing body of evidence has shown that babies are much less likely to be born with HIV if the pregnant parent is on treatment. A study of the French Perinatal Cohort, conducted between 2000 and 2011, is the largest study to show the impact of treatment on preventing HIV transmission to a newborn. This study found that no HIV transmissions occurred among 2,651 infants born to cisgender women who were on treatment before they conceived and throughout their pregnancy, who had an undetectable viral load at delivery and who did not breastfeed.
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If You Have A Negative Test Result Does That Mean That Your Partner Is Hiv
No. Your HIV test result reveals only your HIV status.
HIV is not necessarily transmitted every time you have sex. Therefore, taking an HIV test is not a way to find out if your partner is infected.
It’s important to be open with your partner and ask them to tell you their HIV status. But keep in mind that your partner may not know or may be wrong about their status, and some may not tell you if they have HIV even if they know they’re infected. Consider getting tested together so you can both know your HIV status and take steps to keep yourselves healthy.
A Viral Load Test Will Let You Know If You Are Undetectable
If youre living with HIV and want to know if youre undetectable, the right test for you is Similar to nucleic acid tests to detect HIV infection, HIV viral load tests measure the number of copies of HIV in a milliliter of your blood. Its recommended that people living with HIV getHIV viral load tests generally every 3 to 6 months, in addition toother lab tests that measure your CD4 count and more.
The bottom line is that if youre living with HIV and have an undetectable viral load, you will still test positive for HIV if you get tested. But, this is expected, and doesnt mean that your treatment is not working or that you arent undetectable. As always, check with your HIV care provider if you have questions about what HIV test is right for you, or what types of tests will give you the answers you need to best care for your health.
San Francisco AIDS Foundation offers a variety of free, confidential sexual health services includingHIV and STI testing,linkage to HIV care,PrEP and more.
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Why Does My Doctor Want Me To Go To The Same Laboratory Each Time I Have My Hiv Viral Load Tested
Laboratories may use different methods to measure HIV viral load, so results can vary from lab to lab. When you have a series of viral load tests done, it is advised that you have the tests done by the same method, typically by the same laboratory, so that the results can be compared and interpreted correctly. Tracking increases or decreases of your viral load must be done by the same method to provide an accurate picture of whether the virus is replicating or staying stable with the current therapy.
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What Is Involved In The Consistent And Correct Use Of Hiv Treatment To Maintain An Undetectable Viral Load For Hiv Prevention
The consistent and correct use of HIV treatment to maintain an undetectable viral load includes:
- high adherence to medications, to achieve and maintain an undetectable viral load
- regular medical appointments to monitor viral load and receive adherence support, if needed
Regular testing and treatment for sexually transmitted infections is also important because HIV treatment does not protect against STIs.
A person on HIV treatment needs to work with their doctor to determine an appropriate schedule for medical checkups and viral load monitoring.
You Cant Get Hiv From Just Any Kind Of Contact
Myths still abound about HIV/AIDS. For example, you cant get HIV from insect bites or stings, hugging, shaking hands, or sharing toilets or dishes, according to the CDC. You also cant get infected from a closed-mouth kiss or contact with an infected persons sweat or tears. You cant get it by simply working or hanging out with someone who has AIDS or is HIV positive, either. HIV transmission from one woman to another woman through sexual contact is also rare, the CDC says.
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Hiv Stigma And Discrimination
HIV can prompt intense feelings in people, regardless of their HIV status. It is sometimes viewed with a sense of unacceptability or disgrace. A person with HIV may feel shame and despair about their status. An HIV-negative person may be fearful or angry when they discover someone has HIV. The relationship of these feelings to HIV is referred to as stigma.Felt stigma refers to deep feelings of shame and self-loathing, and the expectation of discrimination. It can have serious negative impacts on the health and wellbeing of people living with HIV by discouraging them from getting tested, receiving support, or taking treatment. It may also lead people to engage in high-risk behaviours that harm their health, and contribute to new HIV infections.Enacted stigma is the experience of unfair treatment by others. For people living with HIV this can be in the form of being treated differently and poorly, or through rejection, abuse, or discrimination.HIV stigma is particularly harmful when it overlaps with other factors that are stigmatised such as if a person uses drugs, is a sex worker, is trans or gender diverse.Breaking down stigma is a community response where:
If you have experienced stigma or discrimination from a health care provider, and are unable to resolve your complaint with them directly, contact the Health Complaints Commissioner
How Is Genital Herpes Diagnosed
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HSV nucleic acid amplification tests are the most sensitive and highly specific tests available for diagnosing herpes. However, in some settings viral culture is the only test available. The sensitivity of viral culture can be low, especially among people who have recurrent or healing lesions. Because viral shedding is intermittent, it is possible for someone to have a genital herpes infection even though it was not detected by NAAT or culture. 11
Type-specific virologic tests can be used for diagnosing genital herpes when a person has recurrent symptoms or lesion without a confirmatory NAAT, culture result, or has a partner with genital herpes. Both virologic tests and type-specific serologic tests should be available in clinical settings serving patients with, or at risk for, sexually transmitted infections. 11
Given performance limitations with commercially available type-specific serologic tests , a confirmatory test with a second method should be performed before test interpretation. If confirmatory tests are unavailable, patients should be counseled about the limitations of available testing before serologic testing. Healthcare providers should also be aware that false-positive results occur. In instances of suspected recent acquisition, serologic testing within 12 weeks after acquisition may be associated with false negative test results. 11
Providers are strongly encouraged to look at CDCs STI Treatment Guidelines for further diagnostic considerations.
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Myths About The Hpv Virus:
1. HPV is rare
Quite the opposite. Its actually really common, so common in fact that four in every five people will have the virus at some point in their lives. This is why clueing ourselves up on the virus is so important.
2. HPV is something to worry about
There are over 100 types of HPV and the majority are nothing to worry about. There are, however, at least 13 high risk types that can cause cancer. That’s can, not will. In most cases, if you or any partners get high-risk HPV your bodies will be able to clear the infection, just like it does with any low risk infections. In a few cases the infection can cause abnormalities in the cells of the cervix which, if not detected and monitored, may develop in to cervical cancer. This is why it is important to attend your smear tests when invited, so that any abnormal cells can be caught before they get the chance to develop into cancer.
3. You will know if you have HPV
False. HPV normally has no signs or symptoms so it is very difficult to tell if someone has it. By attending your regular smear tests, high-risk HPV infection and any abnormalities caused by the infection can be identified and treated if needed.
4. Only promiscuous people get HPV
5. HPV is a young persons virus
6. You wont get HPV if youre healthy
7. HPV doesnt affect LGBT+ people
8. If you use a condom you wont get HPV
9. Theres no relationship between smoking and HPV infection
10. The HPV vaccine means you wont get HPV
11. It only affects women